Product Description

CDX2 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66550-50, MB66550-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CDX2, a homeobox domain-containing transcription factor, is a master regμlator of the trophectoderm, the layer that gives rise to extra-embryonic tissues in mammalian development. CDX2 is also involved in intestinal development, and gain of expression or loss of expression has been associated with various human malignancies, such as Barrett's esophagus and colorectal cancer. Mouse embryonic stem cells deficient in CDX2 display limited hematopoietic progenitor development and altered Hox gene expression, pointing to a role for CDX2 in Hox gene regμlation. CDX2 is also implicated in the aberrant expression of Hox genes in human AML cell lines.

Category: Primary Antibody

Reactivity: Human, Mouse, Monkey

Host: Mouse

Applications: WB, IF/ICC, IP

Alternate Names: CDX3, Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human CDX2 protein fragments expressed in E.coli

Dilution: WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of CDX2 protein.

Molecular Weight: ~ 38 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99626

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only