CDX2 Mouse mAb - EM1057

CDX2 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1057-50, EM1057-100

Citations, Manuals and MSDS Available upon request.

Background: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.

Alternate Name: Caudal Type Homeobox Transcription Factor 2 ; CDX3; Homeobox Protein CDX-2

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:1, 000 IHC 1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 42kDa

Human Gene ID: 1045

Human SWISS Prot NO: Q99626

Subcellular Location: Nucleus

Research Use Only