Product Description

CDYL2 Polyclonal Antibody

Catalogue Numbers: BS62337-50, BS62337-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q8N8U2

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC ICC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200 ICC:1:50~1:200

Background: CDY is a gene family expressed exclusively in the testis that localizes to a region of the Y chromosome frequently deleted in infertile males. CDY proteins contain two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and a C-terminal domain, which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY proteins act as histone acetyltransferases with strong preference for Histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein 2 (CDYL2) is a related nuclear protein that is ubiquitously expressed with moderate levels in most tissues. The gene encoding CDYL2 is located on chromosome 16.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CDYL2 polyclonal antibody detects endogenous levels of CDYL2 protein.

Extra Notes: Western blot (WB) analysis of CDYL2 polyclonal antibody at 1:500 dilution
LaneA:CT26 whole cell lysate
LaneB:PC12 whole cell lysate
LaneC:Hela whole cell lysate
LaneD:PC3 whole cell lysate

Bioworld Molecular Weight: ~ 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Chromodomain Y-like protein 2; CDY-like 2; CDYL2

Immunogen: Synthetic peptide, corresponding to Human CDYL2.

Conjugate: Unconjugated

Modification: Unmodified