CDYL2 Polyclonal Antibody - BT-AP01657

CDYL2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01657-20, BT-AP01657-50, BT-AP01657-100

Citations, Manuals and MSDS Available upon request.

Background: CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.

Research Areas: Others

Target Protein: CDYL2

Applications: WB, IHC-p, ICC, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CDYL2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 56501

UniProt Accession: Human: Q8N8U2

Synonyms: CDYL2; Chromodomain Y-like protein 2; CDY-like 2

GeneID: Human: 124359

Research Use Only