CEA Polyclonal Antibody-BS90291

CEA Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90291-50, BS90291-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P06731(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IHC

All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200

Background: The CD66 (carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 family members mediate homotypic and heterotypic intercellular adhesion events. CD66E, also known as CEA, is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CEA polyclonal antibody detects endogenous levels of CEA protein.

Bioworld Molecular Weight: 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining Carcino Embryonic Antigen CEA(CD66e) in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining Carcino Embryonic Antigen CEA(CD66e) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: CEA, CD66e, CEACAM5, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CEA, Ceacam5, CEAM5, DKFZp781M2392, Meconium antigen 100, OTTHUMP00000199032, OTTHUMP00000199033, OTTHUMP00000199034,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified