CEACAM5 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12421-20, A12421-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 77 kDa
Observed Molecular Weight: 180-200 kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1048
SWISS: P06731
Alternate Names: CEA; CD66e; CEACAM5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor immunology, Tumor-associated antigens, Tumor biomarkers, Immunology Inflammation, CDs, Stem Cells, Mesenchymal Stem Cells.
NCBI Alias: CEACAM5
Research Use Only