CEACAM6 Polyclonal Antibody
Catalogue Numbers: BS60595-50, BS60595-100
Sizes: 50µl, 100µl
Alternative Name: Carcinoembryonic antigen-related cell; adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD66c; CEACAM6; NCA
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P40199
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The CD66 (carcinoembryonic antigen, CEA, Biliary glycoprotein I, BGP-1, CECAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2.. CD66a, CD66b, CD66c, CD66d, CD66e and CD66f are the best characterized CD66 antigens, and CD66a-d expression upregulates on the surface of granulocytes upon stimulation. CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CEACAM6 polyclonal antibody detects endogenous levels of CEACAM6 protein.
Bioworld Molecular Weight: ~ 37 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of CEACAM6 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human CEACAM6
Conjugate: Unconjugated
Modification: Unmodified