Product Description

CENP-M Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23227-50, RA23227-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: centromere protein M (CENPM) Homo sapiens The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), WB

Alternate Names: Centromere protein M (CENP-M;Interphase centromere complex protein 39;Proliferation-associated nuclear element protein 1)

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, WB 1:500-2000

Molecular Weight: 20

Protein Molecular Weight (kDa): 20

Storage: -20°C/1 year

Human Gene ID: 79019

Human SwissProt Number: Q9NSP4

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only