CENPC Polyclonal Antibody - E-AB-14864

CENPC Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14864-60, E-AB-14864-120, E-AB-14864-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CENPC

Target Synonym: CENP-C 1; CENP-C; CENPC; CENPC1; Centromere autoantigen C; Centromere autoantigen C1; Centromere protein C 1; Centromere protein C; hcp-4; ICEN7; Interphase centromere complex protein 7; MIF2

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q03188

Background: Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human CENPC

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only