CEP170 Polyclonal Antibody - BT-AP01694

CEP170 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01694-20, BT-AP01694-50, BT-AP01694-100

Citations, Manuals and MSDS Available upon request.

Background: The product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.

Research Areas: Others

Target Protein: CEP170

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CEP170 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 175293

UniProt Accession: Human: Q5SW79; Mouse: Q6A065

Synonyms: CEP170; FAM68A; KAB; KIAA0470; Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein

GeneID: Human: 9859

Research Use Only