Product Description

CEP76 Polyclonal Antibody

Catalogue Numbers: BS62332-50, BS62332-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q8TAP6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP76 (centrosomal protein of 76 kDa) gene encodes a protein of 659 amino acids. The CEP76 protein is homologous among several species including human, mouse, rat and xenopus, suggesting a conserved function.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CEP76 polyclonal antibody detects endogenous levels of CEP76 protein.

Extra Notes: Western blot (WB) analysis of CEP76 polyclonal antibody at 1:500 dilution
LaneA:COS-7 whole cell lysate
LaneB:PC3 whole cell lysate
LaneC:CT26 whole cell lysate
LaneD:PC12 whole cell lysate

Bioworld Molecular Weight: ~ 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Centrosomal protein of 76 kDa; Cep76; CEP76; centrosomal protein 76; C18orf9

Immunogen: Synthetic peptide, corresponding to Human CEP76.

Conjugate: Unconjugated

Modification: Unmodified