CERK Polyclonal Antibody - E-AB-10955

CERK Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10955-60, E-AB-10955-120, E-AB-10955-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CERK

Target Synonym: Acylsphingosine kinase; Ceramide kinase; Cerk; CERK1; dA59H18.2; dA59H18.3; hCERK; KIAA1646; Lipid kinase 4; Lipid kinase LK4; LK4

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8TCT0

Background: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human CERK

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only