CERS6 Polyclonal Antibody - E-AB-16562

CERS6 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16562-60, E-AB-16562-120, E-AB-16562-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CERS6

Target Synonym: Ceramide synthase 6; CerS 6; CERS5; CerS6; LAG1 homolog ceramide synthase 6; LAG1 longevity assurance homolog 6; LASS 6; Lass6; LASS6; Longevity assurance homolog 6; MGC129949; MGC129950; T1L

Research Areas: Cancer, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q6ZMG9

Background: The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human CERS6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only