CFL1 Polyclonal Antibody - E-AB-40164

CFL1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40164-60, E-AB-40164-120, E-AB-40164-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Cofilin-1

Target Synonym: 18 kDa phosphoprotein; CFL 1; CFL; CFL1; COF1; Cofilin 1; Cofilin 1 non muscle; Cofilin; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18

Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P23528

Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Concentration: 2 mg/mL

Immunogen: Recombinant human Homeobox protein Cofilin-1 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 17 kDa

Observed MW: 17 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only