Product Description

CFTR (E733) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1525-50, BS1525-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CFTR, for cystic fibrosis transmembrane conductance regμlator, is a cyclic adenosine monophosphate (cAMP)-regμlated chloride channel protein. CFTR belongs to the MDR subfamily within the ATP-binding transport protein family. It has two transmembrane domains (TMDs), two nucleotide binding domains (NBDs) and one regμlatory domain. Mutations of CFTR are associated with cystic fibrosis (CF), a disease characterized by chronic bronchopμlmonary disease, elevated sweat electrolytes and insufficient pancreatic function. CFTR mutations can also resμlt in congenital bilateral absence of vas deferens (CBAVD), a form of male sterility that a majority of male CF patients exhibit.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Cystic fibrosis transmembrane conductance regμlator, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, cAMP-dependent chloride channel, CFTR, ABCC7

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 700-750 of Human CFTR.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CFTR (E733) polyclonal antibody detects endogenous levels of CFTR protein.

Molecular Weight: ~ 168 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13569

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only