Product Description

CFTR (Phospho-Ser737) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23285-50, RA23285-100

Citations, Manuals and MSDS Available upon request.

Background: cystic fibrosis transmembrane conductance regulator (CFTR) Homo sapiens This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: Cystic fibrosis transmembrane conductance regulator (CFTR;ATP-binding cassette sub-family C member 7;Channel conductance-controlling ATPase;EC 3.6.3.49;cAMP-dependent chloride channel)

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1080

Protein MW (KDa): 166

SWISS: P13569

Source: Rabbit

Research Use Only