Product Description

CGB (D131) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1159-50, BS1159-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01233

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Choriogonadotropin is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a unique β chain and an α chain common to all gonadotropins. The unique β chain confers biological specificity to choriogonadotropin, luteinizing hormone and follicle stimulating hormone. The secreted α subunit maps to human chromosome 6 and the β subunit of choriogonadotropin maps to human chromosome 19. Choriogonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone. Choriogonadotropin is a member of the cystine knot growth-factor superfamily, a group of proteins that contain a distinct arrangement of six cysteine residues and are expressed in placenta. The proper secretion and dimerization of choriogonadotropin depends on the conformation of the cystine knot, although biological activity is independent of this conformation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of CGB (D131) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 18 kDa

Specificity: CGB (D131) polyclonal antibody detects endogenous levels of Choriogonadotropin subunit beta protein.

Alternative Name: CG beta; CG-beta; CGB 3; CGB 5; CGB 7; CGB; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin subunit beta; Chorionic gonadotrophin chain beta; Chorionic gonadotropin beta 3 subunit; Chorionic gonadotropin beta 3 subunit precursor; Chorionic gonadotropin beta chain; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta subunit; hCGB; Choriogonadotropin β; hCG beta

Immunogen: Synthetic peptide, corresponding to amino acids 101-150 of Human CGB.

Conjugate: Unconjugated

Modification: Unmodified