CGI-43 Polyclonal Antibody - BT-AP01735

CGI-43 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01735-20, BT-AP01735-50, BT-AP01735-100

Citations, Manuals and MSDS Available upon request.

Background: CCZ1, also known as CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae), CCZ1A, CCZ1B or CGI-43, is a 482 amino acid protein that localizes to the lysosomal membrane and belongs to the CCZ1 family. CCZ1 is encoded by a gene that maps to human chromosome 7, which houses over 1000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Research Areas: Others

Target Protein: CCZ1

Applications: WB, ELISA

Reactivity: Human, Mouse, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CGI-43 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 55866

UniProt Accession: Human: P86791/P86790

Synonyms: CCZ1; C7orf28A; CGI-43; Vacuolar fusion protein CCZ1 homolog; CCZ1B; C7orf28B; Vacuolar fusion protein CCZ1 homolog B; Vacuolar fusion protein CCZ1 homolog-like

GeneID: Human: 221960; Mouse: 231874

Research Use Only