CHAT Polyclonal Antibody - E-AB-70028

CHAT Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-70028-60, E-AB-70028-120, E-AB-70028-200 Citations, Manuals and MSDS Available upon request. Abbreviation: CHAT Target Synonym: Acetyl CoA choline O acetyltransferase; Acetyl CoA:choline O acetyltransferase; Chat; CHOACTase; Choline acetylase; choline acetyltransferase; Choline O acetyltransferase; Choline O-acetyltransferase; CLAT; CMS1A; CMS1A2; EC 2.3.1.6; OTTHUMP00000019583; OTTHUMP00000019584 Research Areas: Cancer, Neuroscience Conjugation: Unconjugated Host: Rabbit Species Reactivity: Mouse, Rat Application: IHC Isotype: IgG Clonality: Polyclonal UNIProt ID: P28329,Q03059,P32738 Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.  Concentration: 350 μg/mL Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CHAT Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 Purification Method: Affinity purification Dilution: IHC 1:100-1:500 Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only