CHD3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2221-20, A2221-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 227kDa
Observed Molecular Weight: 280kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 1107
SWISS: Q12873
Alternate Names: ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA; CHD3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:200 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Chromatin Remodeling, Immunology Inflammation.
NCBI Alias: CHD3
Research Use Only