Product Description

CHD4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63554-60, E-AB-63554-120, E-AB-63554-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CHD4

Target Synonym: CHD4; CHD-4; Mi-2b; Mi2-BETA; SIHIWES

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q14839

Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CHD4 (NP_001264.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:100-1:200 IF 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only