Chemokine Receptor D6 Polyclonal Antibody - BT-AP01753

Chemokine Receptor D6 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01753-20, BT-AP01753-50, BT-AP01753-100

Citations, Manuals and MSDS Available upon request.

Background: CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. CCBP2 is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. CCBP2 is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Research Areas: Immunology

Target Protein: CCBP2

Applications: IF, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Chemokine Receptor D6 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 43443

UniProt Accession: Human: O00590; Mouse: O08707

Synonyms: CCBP2; CCR10; CMKBR9; Chemokine-binding protein 2; C-C chemokine receptor D6; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine-binding protein D6

GeneID: Human: 1238

Research Use Only