Product Description

CHI3L1 Polyclonal Antibody

Catalogue Numbers: BS60625-50, BS60625-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P36222

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CHI3L1 polyclonal antibody detects endogenous levels of CHI3L1 protein.

Extra Notes: Western blot (WB) analysis of CHI3L1 pAb at 1:500 dilution
Lane1:U-87MG whole cell lysate(40ug)
Lane2:L02 whole cell lysate(40ug)
Lane3:AML-12 whole cell lysate(40ug)
Lane4:C6 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Chitinase-3-like protein 1; 39 kDa synovial protein; Cartilage glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1

Immunogen: A synthetic peptide corresponding to residues in Human CHI3L1

Conjugate: Unconjugated

Modification: Unmodified