CHIP rabbit pAb - ES11301

CHIP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11301-50, ES11301-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 160-240

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 33kD

Human Gene ID: 10273

Human SWISS Prot NO: Q9UNE7

Subcellular Location: Cytoplasm. Nucleus. Translocates to the nucleus in response to inflammatory signals in regulatory T-cells (Treg).

Research Use Only