CHIT1 Monoclonal Antibody - BT-MCA4304

CHIT1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4304-50, BT-MCA4304-100

Citations, Manuals and MSDS Available upon request.

Background: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Research Areas: Immunology

Target Protein: CHIT1

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1D9G2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CHIT1

Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 52kDa

UniProt Accession: Q13231

Synonyms: Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1

GeneID: 1118

Research Use Only