Chk2 Monoclonal Antibody-MB10732

Chk2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10732-50, MB10732-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O96017

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Chk2 in HCT116 using Chk2 antibody, and DAPI., Western blot analysis of Chk2 in Jurkat lysates using Chk2 antibody.

Alternative Name: CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

Immunogen: Recombinant protein of human Chk2

Conjugate: Unconjugated

Modification: Unmodified