Product Description

CHMP2A Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS71739-50, BS71739-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43633

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CHMP2A polyclonal antibody detects endogenous levels of CHMP2A protein.

Bioworld Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using CHMP2A antibody.

Alternative Name: BC2; BC-2; VPS2; CHMP2; VPS2A;

Immunogen: Recombinant protein of human CHMP2A

Conjugate: Unconjugated

Modification: Unmodified