Product Description

CHN2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92958-60, E-AB-92958-120, E-AB-92958-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CHN2

Target Synonym: CHN2; ARHGAP3; BCH; CHN2-3; RHOGAP3

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P52757

Background: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CHN2

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Calculated MW: 27kDa/31kDa/33kDa/37kDa/38kDa/53kDa/62kDa

Observed MW: 54kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only