Choactase Polyclonal Antibody - BT-AP01772

Choactase Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01772-20, BT-AP01772-50, BT-AP01772-100

Citations, Manuals and MSDS Available upon request.

Background: CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform.

Research Areas: Neuroscience

Target Protein: CHAT

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Choactase Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 82568/74361/70394

UniProt Accession: Human: P28329; Mouse: Q03059; Rat: P32738

Synonyms: CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase

GeneID: Human: 1103

Research Use Only