Choactase Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23335-50, RA23335-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: choline O-acetyltransferase (CHAT) Homo sapiens This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: CHAT, Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 82, 70 Protein Molecular Weight (kDa): 82, 70 Storage: -20°C/1 year Human Gene ID: 1103 Human SwissProt Number: P28329 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only