Choactase rabbit pAb - ES1975

Choactase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1975-50, ES1975-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],

Alternate Name: CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Choactase. AA range:334-383

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 82, 70kD

Human Gene ID: 1103

Human SWISS Prot NO: P28329

Subcellular Location: nucleus, cytoplasm, cytosol, presynapse,

Research Use Only