CHOP Mouse Monoclonal Antibody (1E1) - RA10980

CHOP Mouse Monoclonal Antibody (1E1)

Size: 50μL, 100μL

Catalogue Numbers: RA10980-50, RA10980-100

Citations, Manuals and MSDS Available upon request.

Background: DNA damage inducible transcript 3 (DDIT3) Homo sapiens This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 1649

Protein MW (KDa): 27

SWISS: P35638

Source: Mouse

Research Use Only