Product Description

Chordin Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65703-50, BS65703-100

Swiss-Prot: Q9H2X0

Host: Rabbit

Chordin Polyclonal Antibody-BS65703

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

Applications: WB,

All Applications: WB=1:500-2000

Background: The patterning of the CNS relies on the interaction of multiple signaling molecules such as Sonic Hedgehog, Wnts, and BMPs and their antagonists Chordin and Noggin. At midgastrula, expression of Noggin overlaps that of Chordin. Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The gene which encodeschordin maps to human chromosome 3q27. Noggin is a secreted protein that binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily of signaling proteins, such as BMP-2,4,7. The gene which encodes noggin maps to human chromosome 17q22.

Purification and Purity: affinity purified by Protein A

Specificity: Chordin Polyclonal Antibody detects endogenous levels of Chordin protein.

Bioworld Molecular Weight: 99kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- Chordin at 1/1000 dilution, Primary: Anti- Chordin at 1/1000 dilution

Alternative Name: Chordin; Chrd; CHRD_HUMAN; MGC133038; Shortgastrulation protein; SOG

Immunogen: KLH conjugated synthetic peptide derived from human Chordin:412-490/951 

Modification: Unmodified

Conjugate: Unconjugated