Product Description

Chordin Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65703-50, BS65703-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The patterning of the CNS relies on the interaction of mμltiple signaling molecμles such as Sonic Hedgehog, Wnts, and BMPs and their antagonists Chordin and Noggin. At midgastrμla, expression of Noggin overlaps that of Chordin. Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The gene which encodeschordin maps to human chromosome 3q27. Noggin is a secreted protein that binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily of signaling proteins, such as BMP-2, 4, 7. The gene which encodes noggin maps to human chromosome 17q22.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: Chordin, Chrd, CHRD_HUMAN, MGC133038, Shortgastrμlation protein, SOG

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Chordin:412-490/951 

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Chordin Polyclonal Antibody detects endogenous levels of Chordin protein.

Molecular Weight: 99kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H2X0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only