Product Description

CHRAC1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61067-50, BS61067-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regμlators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex), which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodelling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregμlar chromatin into a regμlar array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regμlarly spaced array. In the presence of CHRAC, the nucleosomal ATPase ISWI catalyses several ATP-dependent transitions of chromatin structure.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Chromatin accessibility complex protein 1, CHRAC-1, Chromatin accessibility complex 15 kDa protein, CHRAC-15, HuCHRAC15, DNA polymerase epsilon subunit p15, CHRAC1, CHRAC15

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CHRAC1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CHRAC1 polyclonal antibody detects endogenous levels of CHRAC1 protein.

Molecular Weight: ~ 15 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NRG0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only