Product Description

CHRDL2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65872-50, BS65872-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q6WN34

Host: Rabbit

Reactivity: Human, Mouse, Rat,Cow,Sheep,

Applications: WB

All Applications: WB=1:500-2000

Background: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. A member of the chordin family of proteins, it contains a signal peptide and three CR (cysteine-rich repeat) domains. When expressed as a recombinant protein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -45°C long term. Avoid freeze-thaw cycles.

Specificity: CHRDL2 Polyclonal Antibody detects endogenous levels of CHRDL2 protein.

Bioworld Molecular Weight: ~45kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- CHRDL2 at 1/1000 dilution

Alternative Name: BNF1; Breast tumor novel factor 1; CHL2; chordin like 2; Chordin like protein 2 precursor; Chordin related protein 2; CRDL2_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human CHRDL2:351-429/429

Conjugate: Unconjugated

Modification: Unmodified