Product Description

CHRDL2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65872-50, BS65872-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. A member of the chordin family of proteins, it contains a signal peptide and three CR (cysteine-rich repeat) domains. When expressed as a recombinant protein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially resμlts in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Cow, Sheep

Host: Rabbit

Applications: WB

Alternate Names: BNF1, Breast tumor novel factor 1, CHL2, chordin like 2, Chordin like protein 2 precursor, Chordin related protein 2, CRDL2_HUMAN.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human CHRDL2:351-429/429

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: CHRDL2 Polyclonal Antibody detects endogenous levels of CHRDL2 protein.

Molecular Weight: ~45kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -45°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6WN34

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only