Product Description

CHRNA10 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-15793-60, E-AB-15793-120, E-AB-15793-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CHRNA10

Target Synonym: Acetylcholine receptor; neuronal nicotinic; alpha-10 subunit; ACH10; Alpha 10 nAChR; Cholinergic receptor nicotinic alpha 10; Cholinergic receptor; neuronal nicotinic; alpha polypeptide 10; Cholinergic receptor; nicotinic; alpha polypeptide 10; CHRNA 10; CHRNA10; NACHR alpha 10; NACHR alpha-10; NACHRA10; Neuronal acetylcholine receptor protein subunit alpha 10; Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha 10; Nicotinic acetylcholine receptor subunit alpha-10; OTTHUMP00000013620

Research Areas: Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9GZZ6

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human CHRNA10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only