Product Description

CHST6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61148-50, BS61148-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Sμlfotransferase enzymes catalyze the sμlfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Carbohydrate sμlfotransferase 5 (CHST5) (also referred to as GlcNAc6ST-3 or IGn6ST) and carbohydrate sμlfotransferase 6 (CHST6) (also referred to as GlcNAc6ST-5 or Cgn6ST) are predominantly expressed in the intestine and cornea, respectively. They are highly homologous and both are orthologs of the murine CHST5. CHST5 and CHST6 may be the resμlt of gene duplication. They catalyze the transfer of sμlfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. CHST5 preferably mediates the sμlfation of short carbohydrates and O-linked sugars of mucin-type acceptors. CHST6 mediates the sμlfation of keratan in the cornea, which is important in maintaining corneal transparency.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: Carbohydrate sμlfotransferase 6 (EC:2.8.2.-), Corneal N-acetylglucosamine-6-O-sμlfotransferase, C-GlcNAc6ST, hCGn6ST, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sμlfotransferase 4-beta, GST4-beta, N-acetylglucosamine 6-O-sμlfotransferase 5, GlcNAc6ST-5, Gn6st-5, CHST6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CHST6.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CHST6 polyclonal antibody detects endogenous levels of CHST6 protein.

Molecular Weight: ~ 52kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9GZX3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only