CHSY2 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23351-50, RA23351-100
Citations, Manuals and MSDS Available upon request.
Background: catalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan.,catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan.,cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt.,function:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer.,online information:GlycoGene database,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,subunit:Binds CHSY1.,tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.,
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: CHPF; CSS2; Chondroitin sulfate synthase 2; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-pro
Applications: WB; IHC-p; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 79586
Protein MW (KDa): 85
SWISS: Q8IZ52
Source: Rabbit
Research Use Only