CHSY2 rabbit pAb - ES7583

CHSY2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7583-50, ES7583-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl-proteoglycan., catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan., cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt., function:Has both beta-1, 3-glucuronic acid and beta-1, 4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer., online information:GlycoGene database, PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., subunit:Binds CHSY1., tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.,

Alternate Name: CHPF; CSS2; Chondroitin sulfate synthase 2; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-pro

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CHSY2. AA range:631-680

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 79586

Human SWISS Prot NO: Q8IZ52

Subcellular Location: [Isoform 1]: Golgi apparatus Golgi stack membrane; Single-pass type II membrane protein. Cytoplasm, cytosol.; [Isoform 3]: Cytoplasm, cytosol. Mitochondrion.; [Isoform 2]: Mitochondrion matrix.

Research Use Only