Chymase rabbit pAb - ES3853

Chymase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3853-50, ES3853-100

Citations, Manuals and MSDS Available upon request.

Background: chymase 1 (CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],

Alternate Name: CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from the Internal region of human Chymase.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 27kD

Human Gene ID: 1215

Human SWISS Prot NO: P23946

Subcellular Location: Secreted. Cytoplasmic granule. Mast cell granules.

Research Use Only