Product Description

CIAPIN1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8142-50, BS8142-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The name of the protein Anamorsin, also designated cytokine-induced apoptosis inhibitor 1 (CIAPIN1), comes from the Latin term “ana-mors-in”, meaning “anti-death molecμle”. During hematopoiesis, Anamorsin is crucial for mediating the anti-apoptotic effects of various cytokines. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Anamorsin is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regμlatory molecμles of the Bcl-2 or CASP families, or to signal transduction molecμles. Anamorsin expression in mouse cells confers resistance to apoptosis caused by IL-3 (interleukin-3) deprivation. Studies demonstrate that the addition of growth factors, such as EPO (erythropoietin), SCF (stem cell factor), TPO (thrombopoietin) or IL-3, all of which depend on RAS signaling, induce dose-dependent expression of Anamorsin in mouse cells.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog, CIAPIN1, CUA001, PRO0915

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human CIAPIN1.

Dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CIAPIN1 polyclonal antibody detects endogenous levels of CIAPIN1 protein.

Molecular Weight: ~ 39 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6FI81

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only