Product Description

Cip4 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46339-50, BS46339-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Required for translocation of GLUT4 to the plasma membrane in response to insμlin signaling (By similarity). Required to coordinate membrane tubμlation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4, 5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubμles. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubμles to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: STP, CIP4, HSTP, STOT, TRIP-10

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Cip4

Dilution: WB: 1:1000-1:5000 IHC: 1:20-1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 80 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15642

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only