Product Description

CIRBP Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10739-50, MB10739-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q14011

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 19 kDa; Observed MW: 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CIRBP in Hela lysates using CIRBP antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using CIRBP antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: CIRP

Immunogen: Recombinant protein of human CIRBP

Conjugate: Unconjugated

Modification: Unmodified