CIS Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23365-50, RA23365-100
Citations, Manuals and MSDS Available upon request.
Background: cytokine inducible SH2 containing protein (CISH) Homo sapiens The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Cytokine-inducible SH2-containing protein (CIS;CIS-1;Protein G18;Suppressor of cytokine signaling;SOCS)
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 1154
SWISS: Q9NSE2
Source: Rabbit
Research Use Only