CIS rabbit pAb - ES8670

CIS rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8670-50, ES8670-100

Citations, Manuals and MSDS Available upon request.

Background: cytokine inducible SH2 containing protein (CISH) Homo sapiens The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Alternate Name: Cytokine-inducible SH2-containing protein (CIS; CIS-1; Protein G18; Suppressor of cytokine signaling; SOCS)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 30-90

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1154

Human SWISS Prot NO: Q9NSE2

Subcellular Location: cytoplasm, cytosol, plasma membrane,

Research Use Only