CK-19 Monoclonal Antibody - E-AB-70231

CK-19 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70231-60, E-AB-70231-120, E-AB-70231-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CK-19

Target Synonym: 40 kDa keratin intermediate filament; CK 19; CK-19; CK19; Cytokeratin 19; Cytokeratin-19; K19; K1C19; K1CS; Keratin 19; Keratin type I 40 kD; Keratin type I 40kD; Keratin type I cytoskeletal 19; Keratin; type I cytoskeletal 19; Keratin; type I; 40 kd; Keratin-19; KRT19; MGC15366

Research Areas: Cancer, Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Monoclonal

Clone No.: 6D6G12

UNIProt ID: P19001,Q63279

Background: The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.

Concentration: 1.1 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 19

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:500-1:2000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only