Product Description

CK-7 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70293-60, E-AB-70293-120, E-AB-70293-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CK-7

Target Synonym: CK 7; CK-7; CK7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K2C7; K7; Keratin 7; Keratin 7; type II; Keratin type II cytoskeletal 7; Keratin; 55K type II cytoskeletal; Keratin; simple epithelial; Keratin; simple epithelial type I; K7; Keratin; type II cytoskeletal 7; Keratin-7; Krt2-7; KRT7; MGC11625; MGC129731; MGC3625; Sarcolectin; SCL; Type II mesothelial keratin K7; Type-II keratin Kb7

Research Areas: Cancer, Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Monoclonal

Clone No.: 7D8G8

UNIProt ID: P08729,Q9DCV7,Q6IG12

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.

Concentration: 2.8 mg/mL

Immunogen: Recombinant protein corresponding to Mouse Cytokeratin 7

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:500

Calculated MW: 51kDa

Observed MW: 51kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only