Product Description

CK8 (Keratin 8) Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4129-25, MB4129-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellμlar structural integrity and also functions in signal transduction and cellμlar differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Category: Primary Antibody

Reactivity: Human, Dog, Monkey, Mouse, Rat

Host: Mouse

Applications: IF, IHC, WB

Alternate Names: CARD2, CK-8, CK8, CYK8, K2C8, K8, KO

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.

Dilution: WB 1:500~1000, IHC 1:50, IF 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2a

Molecular Weight: 53.5 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05787

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only