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CKAP5 Rabbit Polyclonal Antibody - RA23392
CKAP5 Rabbit Polyclonal Antibody - RA23392
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CKAP5 Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23392-50, RA23392-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000
Applications: WB
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 9793
SWISS: Q14008
Source: Rabbit
Research Use Only
