Product Description

Cks1 (H3) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2290-50, BS2290-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Cdc2 p34-cyclin B complex plays a critical role in the cell cycle by regμlating the G2 to M transition. Also referred to as M-phase promoting factor or MPF, this complex is a required component of the cell cycle machinery and is necessary for cell entry into mitosis. The Cdc28 protein represents the S. cerevisiae counterpart of human Cdc2 p34 and has been found complexed to a regμlatory protein, termed p13suc 1, in addition to cyclin B. The human homolog of p13suc 1 has been identified and designated Cks1 p9. Nμll mutations in the p13suc 1 and Cks1 p9 genes resμlt in the arrest of the cell cycle at either the G1 or G2 phase, suggesting that the proteins may also regμlate the activity of cyclin dependent kinases that act at critical points early in the cell cycle.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC, IF

Alternate Names: Cyclin-dependent kinases regμlatory subunit 1, CKS-1, CKS1B, CKS1, PNAS-143, PNAS-16

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to the N-terminual of Human Cks1.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cks1 (H3) polyclonal antibody detects endogenous levels of Cks1 protein.

Molecular Weight: ~ 9 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P61024

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only